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by Bill Roberts - aka Anavar, Oxandrin. Unlike
most oral steroids, which are Class II steroids
giving most of their anabolic effect by means other
than the androgen receptor (AR), it seems that oxandrolone
probably does have good binding to the AR, and is
therefore a Class I steroid, while having little
other effect. By itself it is considered to be a
weak anabolic.
Partly this is due to its apparent lack of non-AR-mediated
activity. This can be corrected of course by stacking
with a Class II steroid such as
Dianabol,
Anadrol®, 4-AD, or nor-4-AD:
the latter two steroids require high blood levels
which are not obtained by oral use of the powders.
The other part of the reason for this is that
bodybuilders make unfortunate and unreasonable comparisons
when judging anabolic steroids. If say 8 tablets
per day does little, then the drug is pronounced
useless or weak by the user. But that is only 20
mg/day, or 140 mg/week. Does 140 mg/week testosterone
give much results? No. Few anabolic steroids
give dramatic results at that dose. Per milligram
the potency is reasonable, but each individual tablet
is weak because the dosage is small.
Because of its high price, very few bodybuilders
have taken large doses of oxandrolone. There is
a single case in the medical literature (Forbes
et al.) where it is reported that a competitive
athlete self-administered 150 mg oxandrolone per
day with remarkable gains. This is of uncertain
credibility because unless urinalysis was done to
verify that no other steroids were taken, there
is no way to be certain that the athlete did not
actually take more drugs than he reported. In any
case, at current prices, only the quite wealthy
could afford such a dose. I personally have tried
150 mg/day and considered it somewhat effective,
but not dramatically so, and not a preferred regimen.
Oxandrolone does not aromatize or convert to DHT,
and has a longer half life than Dianabol - 8 hours
vs. 4 hours. Thus, a moderate dose taken in the
morning is largely out of the system by night, yet
supplies reasonable levels of androgen during the
day and early evening.
Oxandrolone shares the liver toxicity problems
common to 17-alkylated steroids. At one time it
was thought that it did not, but both clinical and
practical experience with Oxandrin has shown that
at doses of 40 mg/day and higher, liver toxicity
is indeed an issue with prolonged use.
Primobolan, I believe,
should be considered a superior compound, offering
the same activity at (usually) a lower price and
without the alkylated-toxicity issue.
Oxandrolone is the chemical
name of active ingredient in Oxandrin and Anavar.
Oxandrin is a registered trademark of Bio-Technology
General Corp. in the United States and/or other
countries. Anavar was originally the registered
trademark of Searle Laboratories.
Oxandrolone Resources
Oxandrolone Pictures
Oxandrin Prescribing Information
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|
| Substance name |
Oxandrolone [USAN:INN] |
| Chemical name |
17ß-hydroxy-17a-methyl-2-oxa-5a-androstan-3-one
|
| Systematic name |
N/A |
| Index name |
2-Oxaandrostan-3-one, 17-hydroxy-17-methyl-,
(5alpha,17beta)- |
| CAS number |
53-39-4 |
| Merck Index Number |
Merck 11, 6875 |
| Molecular formula |
C19-H30-O3 |
| Molecular weight |
306.443 g/mol |
| Legal status |
Prescription
only (US); DEA Schedule III (US) |
| Routes of administration |
Oral |
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Beyond Steroids by Anthony Roberts - The Newest and Most Effective Bodybuilding
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Burn the
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Chemical Muscle Enhancement by Author L Rea - Bodybuilder's Desk Reference
Chemical Wizardry by George Spellwin - The Definitive Anabolic Steroid and
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The Layman's Guide
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